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名稱	Recombinant Human IL-15
型號(hào)
更新時(shí)間	2023-09-24
特點(diǎn)	IL-15 細(xì)胞因子,刺激T淋巴細(xì)胞的增殖和與IL-2許多生物學(xué)性質(zhì)。主要在T細(xì)胞IL-15發(fā)揮其生物活性。也很重要的發(fā)展,生存和NK細(xì)胞的活化。增加表達(dá)IL-15牽連了風(fēng)濕性關(guān)節(jié)炎、炎癥性腸病和艾滋病和HTLV-I隸屬于逆轉(zhuǎn)錄病毒疾病。人類IL-15生物活性在小鼠細(xì)胞的劑量依賴性刺激老鼠的CTLL細(xì)胞的擴(kuò)散。重組人類IL-15 12.9 kDa蛋白由115個(gè)氨基酸殘基組成。使用所有無(wú)動(dòng)物生產(chǎn)試劑}

詳細(xì)內(nèi)容

一.產(chǎn)品名稱：Recombinant Human IL-15/重組IL-15

二.Catalog Number:AF-200-15

三.Synonyms:IL-T

四.Description:

IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activities primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowel disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant human IL-15 is a 12.9 kDa protein consisting of 115 amino acid residues. Manufactured using all non-animal reagents.

五.AA Sequence:

MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISLESGDASI HDTVENLIIL ANNSLSSNGN VTESGCKECE ELEEKNIKEF LQSFVHIVQM FINTS

六.Source:E.coli

七.Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.

八.Biological Activity:

Determined by its ability to stimulate the proliferation of mouse CTLL-2 cells. The expected ED₅₀ is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥2 x 10⁶ units/mg.

九.Cross Reactivity:Monkey, Mouse, Human, Human + Mouse